Primary Class of Medications Responsible for
Photosensitizing Reactions
(Examples by Generic Name)
Jerome I. Levine, M.S.,
R.Ph., prepared the following list for the Federal Drug Administration. The
list was published under the title "Medications That Increase Sensitivity
To Light: A 1990 Listing." The FDA has confirmed this list to be the most
recent.
The mention of commercial products, their sources, or their use in connection with material reported herein is not to be construed as either an actual or implied endorsement of such products by the Department of Health and Human Services.
The following medications have been reported by the U.S. Food and Drug Administration (FDA) as either causing Photosensitivity, Phototoxicity or Photoallergic reactions.
|
Generic Name
|
Brand Name
|
Therapeutic Class
|
| Acetazolamide | Diamox | Anticonvulsant, Antiglaucoma diuretic |
| Amiloride + Hydrochlorothizide | Moduretic | Antihypertensive, Thiazide diuretic |
| Amiodarone | Cordarone (15%) | Antiarrhythmic |
| Amitriptyline | Elavil | Antidepressant (tricyclic) |
| Amitriptyline | Endep | Antidepressant (tricyclic) |
| Amoxapine | Asendin (<1%) | Antidepressant (tricyclic) |
| Astemizole | Hismanal | Antihistamine |
| Atenolol + Chlorthalidone | Tenoretic | Beta-adrenergic blocker Thiazide diuretic |
| Auranofin | Ridaura | Antiarthritic, Gold compound |
| Azatadine | Optimine | Antihistamine |
| Azatidine + Pseudoephedrine | Trinalin | Repetabs Antihistamine, Decongestant |
| Bendroflumethiazide | Naturetin | Antihypertensive, Thiazide diuretic |
| Benzthiazide | Exna | Antihypertensive, Thiazide diuretic |
| Bromodiphenhydramine | Ambenyl | Antihistamine |
| Brompheniramine | Dimetane | Antihistamine |
| Captopril | Capoten | Antihypertensive |
| Captopril + Hydrochlorothiazide | Capozide | Antihypertensive, Thiazide diuretic |
| Carbamazepine | Tegretol | Analgesic, Anticonvulsant |
| Chlordiazepoxide + Amitriptyline | Limbitrol | Antidepressant (tricyclic) Tranquilizer |
| Chlorothiazide | Diuril | Antihypertensive, Thiazide diuretic |
| Chlorpheniramine | Chlorpheniramine | Antihistamine |
| Chlorpheniramin + D-Pseudoephedrine | Deconamine | Antihistamine, Decongestant |
| Chlorpheniramine + Phenylpropanolamine | Ru-Tuss II | Antihistamine, Decongestant |
| Chlorpromazine | Thorazine | Antiemetic, Tranquilizer |
| Chlorpropamide | Diabinese | Antidiabetic (oral), Sulfonylurea |
| Chlorprothixene | Taractan | Antiemetic, Tranquilizer |
| Chlorthalidone | Hygroton | Antihypertensive, Thiazide diuretic |
| Chlorthalidone | Thalitone | Antihypertensive, Thiazide diuretic |
| Chlorthalidone + Reserpine | Demi-Regroton | Antihypertensive, Thiazide diuretic |
| Chlorthalidone + Reserpine | Regroton | Antihypertensive, Thiazide diuretic |
| Ciprofloxacin | Cipro (<1%) | Anti-infective |
| Clemastine | Tavist | Antihistamine |
| Clofazime | Lamprene (<1%) | Antibacterial, Antileprosy agent |
| Clonidine Chlorthalidone + | Combipres | Antihypertensive, Thiazide diuretic |
| Coal Tar | Estar Gel | Antipsoriatic, Eczema |
| Coal Tar | Balnetar | Antipsoriatic, Eczema |
| Contraceptive, oral | Estrogen | Birth control pill, Female sex hormone |
| Cromolyn | Intal Inhaler | Antiasthmatic |
| Cyclobenzaprine | Flexeril | Anti-skeletal, Muscle spasms |
| Cyproheptadine | Periactin | Antihistamine, Antiserotonergic |
| Dacarbazine | DTIC-Dome | Anti-Hodgkin's disease, Antimetabolite |
| Danazol | Danocrine | Gonadotropin inhibitor |
| Demeclocycline | Declomycin | Antibiotic |
| Desipramine | Norpramin | Antidepressant (tricyclic) |
| Desipramine | Pertofrane | Antidepressant (tricyclic) |
| Dexchlorpheniramine | Polaramine | Antihistamine |
| Diclofenac | Voltaren (<1%) | NSAID,* antiarthritic |
| Diflunisal | Dolobid (<1%) | NSAID,* antiarthritic |
| Diltiazem Calcium channel blocker | Cardizem (<1%) | Antianginal, Antihypertensive |
| Diphenhydramine | Benadryl | Antihistamine |
| Diphenylpyraline | Hispril Spansule | Antihistamine |
| Doxepin | Sinequan | Antidepressant (tricyclic) |
| Doxycycline | Vibramycin | Antibiotic |
| Doxycycline Hyclate | Doryx | Antibiotic |
| Enalapril | Vasotec | Antihypertensive |
| Enalapril + Hydrochlorothiazide | Vaseretic | Antihypertensive, Thiazide diuretic |
| Erythromycin Ethylsuccinate + | Pediazole | Antibiotic |
| Estrogens | Contraceptive, oral | Female sex hormone |
| Estrogens | Estrogens | Female sex hormone |
| Ethionamide | Trecator-SC | Anti-infective, Antituberculosis |
| Etretinate | Tegison | Antipsoriatic |
| Floxuridine | FUDR Injectable | Antimetabolite, Antineoplastic |
| Flucytosine | Ancobon | Antifungal |
| Fluorouracil | Adrucil | Antineoplastic |
| Fluorouracil | Efudex | Antineoplastic |
| Fluorouracil | Fluorouracil | Antineoplastic |
| Fluphenazine | Prolixin | Antipsychotic, Tranquilizer |
| Fluphenazine | Permitil | Antipsychotic, Tranquilizer |
| Flurbiprofen | Ansaid | NSAID,* antiarthritic |
| Flutamide | Eulexin | Antimetastatic (prostatic carcinoma) |
| Furosemide | Lasix | Antihypertensive, Diuretic |
| Gentamicin | Garamycin | Antibiotic |
| Glipizide | Glucotrol | Antidiabetic (oral), Sulfonylurea |
| Glyburide | Diabeta | Antidiabetic (oral), |
| Glyburide | Micronase | Antidiabetic (oral), |
| Gold Salts (compounds) | Solganal | Antiarthritic, Gold compound |
| Gold Sodium Thiomalate | Myochrysine | Antiarthritic, Gold compound |
| Griseofulvin | Fulvicin | U/F Antibiotic, Antifungal |
| Griseofulvin Ultramicrosize | Grisactin Ultra | Antibiotic, Antifungal |
| Guanethidine + Hydrochlorothiazide | Esimil | Antihypertensive, Thiazide diuretic |
| Haloperidol | Haldol | Antipsychotic, Tranquilizer |
| Hexachlorophene | Phisohex | Antibacterial |
| Hydralazine + Hydrochlorothiazide | Apresazide | Antihypertensive, Thiazide diuretic |
| Hydralazine | Apresoline-Esidrix | Antihypertensive, Thiazide diuretic |
| Hydrochlorothiazide | Esidrix | Antihypertensive, Thiazide diuretic |
| Hydrochlorothiazide | Hydrodiuril | Antihypertensive, Thiazide diuretic |
| Hydrochlorothiazide | Oretic | Antihypertensive, Thiazide diuretic |
| Hydrochlorothiazide | Oreticyl | Antihypertensive, + Deserpidine |
| Hydrochlorothiazide + Triamterene | Dyazide | Antihypertensive, Thiazide diuretic |
| Hydrochlorothiazide | Maxzide | Antihypertensive, Thiazide diuretic |
| Hydroflumethiazide | Diucardin | Antihypertensive, Thiazide diuretic |
| Hydroflumethiazide | Saluron | Antihypertensive, Thiazide diuretic |
| Hydroflumethiazide + Reserpine | Salutensin/Salutensin-Demi | Antihypertensive, Thiazide diuretic |
| Ibuprofen | Advil (<1%) | NSAID,* antiarthritic |
| Ibuprofen | Motrin (<1%) | NSAID,* antiarthritic |
| Imipramine | Tofranil | Antidepressant (tricyclic) |
| Indapamide | Lozol | Antihypertensive, Diuretic |
| Interferon ALFA-2B | Intron A (<1%) | Antiviral agent |
| Isocarboxazid | Marplan | Antidepressant, MAO inhibitor |
| Isotretinoin | Accutane | Antiacne |
| Ketoprofen | Orudis (<1%) | NSAID,* antiarthritic |
| Labetalol | Normodyne | Antihypertensive,Beta- and alpha-adrenergic blocker |
| Labetalol + Hydrochlorothiazide | Normozide | Beta- and alpha-adrenergic blocker, Thiazide diuretic |
| Labetalol + Hydrochlorothiazide | Trandate HCT | Beta- and alpha-adrenergic blocker, Thiazide diuretic |
| Lisinopril + Hydrochlorothiazide | Prinzide | Antihypertensive, Thiazide diuretic |
| Lisinopril + Hydrochlorothiazide | Zestoretic | Antihypertensive, Thiazide diuretic |
| Lovastatin | Mevacor | Anticholesterol |
| Maprotiline | Ludiomil | Antidepressant |
| Meperidine + Promethiazine | Mepergan | Narcotic analgesic |
| Mesoridazine | Serentil | Antipsychotic, Tranquilizer |
| Methacycline | Rondomycin | Antibiotic |
| Methazolamide | Neptazane | Antiglaucoma |
| Methdilazine | Tacaryl | Antihistamine, Antipruritic |
| Methotrexate | Folex | Antimetabolite, Antipsoriatic |
| Methotrexate | Methotrexate | Antimetabolite, Antipsoriatic |
| Methotrexate | Mexate & Mexate-AQ | Antimetabolite, Antipsoriatic |
| Methyclothiazide | Aquatensen | Antihypertensive, Thiazide |
| Methyclothiazide | Enduron | Antihypertensive, Thiazide diuretic |
| Methyclothiazide + Deserpidine | Enduronyl | Antihypertensive, Thiazide diuretic |
| Methyclothiazide + Reserpine | Diutensen-R | Antihypertensive, Thiazide diuretic |
| Methyldopa + Hydrochlorothiazide | Aldoril | Antihypertensive, Thiazide diuretic |
| Methyldopa + Chlorothiazide | Aldoclor | Antihypertensive, Thiazide diuretic |
| Metolazone | Diulo | Antihypertensive, Thiazide diuretic |
| Metolazone | Mykrox | Antihypertensive, Thiazide diuretic |
| Metolazone | Zaroxolyn | Antihypertensive, Thiazide diuretic |
| Metoprolol + Hydrochlorothiazide | Lopressor HCT | Beta-adrenergic blocker, Thiazide diuretic |
| Minocycline | Minocin | Antibiotic |
| Minoxidol | Rogaine | Hair growth stimulator |
| Nabilone | Cesamet | Antiemetic, Antinausea |
| Nadolol + Bendroflumethiazide | Corzide | Antihypertensive, Beta-adrenergic blocker |
| Nalidixic Acid | NegGram | Antimicrobial |
| Naprosyn | Anaprox | NSAID,* antiarthritic |
| Naprosyn | Naproxen | NSAID,* antiarthritic |
| Nifedipine | Adalat | Antianginal, Antihypertensive, Calcium channel blocker |
| Nifedipine | Procardia | Antianginal, Antihypertensive, Calcium channel blocker |
| Norfloxacin | Noroxin | Antibacterial |
| Nortriptyline | Pamelor | Antidepressant (tricyclic) |
| Oxytetracycline | Terramycin | Antibiotic |
| Perphenazine | Trilafon | Antipsychotic, Tranquilizer |
| Perphenazine + Amitriptyline | Etrafon | Antidepressant (tricyclic) Tranquilizer |
| Phenylbutazone | Butazolidin | NSAID,*antiarthritic |
| Phenylpropanolamine + Chlorpheniramine | Ornade Spansule | Antihistamine, Decongestant |
| Phenylpropanolamine + Pheniramine + Pyrilamine | Triaminic TR | Decongestant, Antihistamine |
| Phenytoin | Dilantin | Anticonvulsant |
| Piroxicam | Feldene | NSAID,* antiarthritic |
| Polythiazide | Renese | Antihypertensive, Thiazide diuretic |
| Prazosin + Polythiazide | Minizide | Antihypertensive, Thiazide diuretic |
| Prochlorperazine | Compazine | Antinausea, Anti-vomiting |
| Promethazine | Phenergan | Antihistamine |
| Propranolol + Hydrochlorothiazide | Inderide | Beta-adrenergic blocker, Thiazide diuretic |
| Protriptyline | Vivactil | Antidepressant (tricyclic) |
| Pyrazinamide | Pyrazinamide | Anti-infective, Antituberculosis |
| Quinethazone | Hydromox | Antihypertensive, Diuretic |
| Quinidine Gluconate | Quinaglute Dura-Tabs | Antiarrhythmic |
| Quinidine Sulfate | Quindex Extentabs | Antiarrhythmic |
| Quinidine Sulfate | Quinora | Antiarrhythmic |
| Quinine | Quinamm | Antiprotozoal |
| Rauwolfia + Serpentina + Bendroflumethiazide | Rauzide | Antihypertensive, Thiazide diuretic |
| Reserpine + Chlorothiazide | Diupres | Antihypertensive, Thiazide diuretic |
| Reserpine + Hydrochlorothiazide | Hydropres | Antihypertensive, Thiazide diuretic |
| Reserpine + Hydrochlorothiazide | Serpasil-Esidrix | Antihypertensive, Thiazide diuretic |
| Reserpine + Hydralazine + Hydrochlorothiazide | Ser-Ap-Es | Antihypertensive, Thiazide diuretic |
| Selegiline | Eldepryl | Anti-Parkinsonism, MAO inhibitor |
| Spironolactone + Hydrochlorothiazide | Aldactazide | Antihypertensive, Thiazide diuretic |
| Sulfacytine | Renoquid | Antibiotic |
| Sulfadoxine + Pyrimethamine | Fansidar | Antimalarial, Antiprotozoal |
| Sulfamethizole + Phenazopyridine | Thiosulfil-A | Urinary analgesic, Antibiotic |
| Sulfamethoxazole | Gantanol | Antibiotic |
| Sulfamethoxazole + Phenazopyridine | Azo Gantanol | Antibiotic, Urinary analgesic |
| Sulfapyridine | (Generic only) | Dermatitis herpetiformis suppressant |
| Sulfasalazine | Azulfidine | Bowel anti-inflammatory |
| Sulfinpyrazone | Anturane | Antigout agent, Antihyperuricemic |
| Sulfasoxazole | Gantrisin | Antibiotic |
| Sulfasoxazole + Phenazopyridine | Azo Gantrisin | Antibiotic, Urinary analgesic |
| Sulfone | Dapsone | Antileprosy, Antimalarial |
| Sunlindac | Clinoril (<1%) | NSAID,* antiarthritic |
| Terfenadine | Seldane | Antihistamine |
| Tetracycline | Achromycin | Antibiotic |
| Thioridazine | Mellaril | Antipsychotic, Tranquilizer |
| Thiothixene | Navane | Antipsychotic, Tranquilizer |
| Timolol + Hydrochlorothiazide | Timolide | Beta-adrenergic blocker, Thiazide diuretic |
| Tolazamide | Tolinase | Antidiabetic (oral), Sulfonylurea |
| Tolbutamide | Orinase | Antidiabetic (oral), Sulfonylurea |
| Tretinoin | Retin-A | Antiacne (topical) |
| Triamterene | Dyrenium | Antihypertensive Diuretic |
| Trifluoperazine | Stelazine | Antipsychotic, Tranquilizer |
| Triflupromazine | Vesprin | Antiemetic, Antipsychotic |
| Trimeprazine | Temaril | Antipsychotic, Tranquilizer |
| Trimethoprim | Trimpex | Antibiotic |
| Trimethoprim + Sulfamethoxazole | Bactrim | Antibiotic |
| Trimethoprim + Sulfamethoxazole | Septra | Antibiotic |
| Trimipramine | Surmontil | Antidepressant (tricyclic) |
| Tripelennamine | PBZ | Antihistamine |
| Triprolidine | Actidil | Antihistamine |
| Triprolidine + Pseudoephedrine | Actifed | Antihistamine, Decongestant |
| Visblastine | Velban | Antieoplastic |
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